hCELA3B, His-Tag; inactive variant S217A Pseudomonas aerigunosa

hCELA3B, His-Tag; inactive variant S217A Pseudomonas aerigunosaThe elastase 3B is relative to pancreatic serine proteinases and has a low level of elastolytic activity comparing to other elastases. Elastase 3B is probably involved in the intestinal transport and metabolism of cholesterol. Furthermore, elastase 3B is an efficient protease that preferentially cleaves proteins after alanine residues due to its alanine specificity. Both elastase 3A and elastase 3B have been referred to as protease E and elastase 1.

Giusi Ianiro

: P2020-128

thereby activating intracellular signaling pathways that mediate regulatory signals

Protein PD-1

as was demonstrated by the emergence of the 2009 pandemic

and multiple sclerosis

have demonstrated remarkable clinical efficacy in various cancer types by unleashing the anti-tumor immune response

Nature (2021)

427 and the related lineage B

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It is the major processing enzyme of the secretory pathway and is localized in the trans-golgi network where it functions to cleave other proteins into their mature/active forms

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